(RNN) - Arizona Sen.John McCain has been diagnosed with brain cancer, CNN reported Wednesday.
The six-term U.S. senator, 80, had surgery Friday to remove a nearly 2-inch blood clot from above his left eye.
His doctors had described the surgery as "minimally invasive."
"Subsequent tissue pathology revealed that a primary brain tumor known as a glioblastoma was associated with the blood clot," said a Mayo Clinic Hospital in Phoenix news release.
"The senator and his family are reviewing further treatment options with his Mayo Clinic care team. Treatment options may include a combination of chemotherapy and radiation."
A statement earlier Wednesday said McCain was "in good spirits and recovering comfortably at home with his family."
McCain had three other malignant melanomas, none invasive, removed in previous years, CNN reported.
He was the Republican nominee for president in 2008.
His daughter, Meghan McCain, issued a statement on Twitter saying her father "is the toughest person I know."
— Meghan McCain (@MeghanMcCain) July 20, 2017
Senate Majority Leader Mitch McConnell tweeted that McCain is "a hero to our country. He has never shied from a fight and I know that he will face this challenge with the same extraordinary courage that has characterized his life."
— Leader McConnell (@SenateMajLdr) July 20, 2017
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